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p300

The p300-CBP coac†ïvâ†ør family in humans is composed of two closely related transcriptional co-activating proteins (or coac†ïvâ†ørs):

p300 (also called EP300 or E1A binding protein p300)
CBP (also known as CREB-binding protein or CREBBP)Both p300 and CBP interact with numerous transcription factors and act to increase the expression of their target genes.

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